TEHRAN — The U.S. and Israel launched a major attack on targets across Iran on Saturday.

U.S. President Donald Trump urged Iranians to take cover during the strikes, but then: “When we are finished, take over your government. It will be yours to take.” It was an extraordinary appeal that suggested the allies could be seeking to end of the country’s theocracy after decades of tensions.

In a video posted on social media, Trump claimed Iran has continued to develop its nuclear program and plans to develop missiles to reach the U.S.

The first strikes of the attack appeared to target the compound home to Iran’s 86-year-old Supreme Leader Ayatollah Ali Khamenei in downtown Tehran. It wasn’t immediately clear if he was there at the time. Smoke could be seen rising from the Iranian capital.

The attack quickly expanded beyond Iran. Iran’s paramilitary Revolutionary Guard said it responded by launching a “first wave” of drones and missiles targeting Israel, where a nationwide warning was issued as the military said it bring down Iranian fire.